Un Unbelievable Intradural Extramedullary Metastasis from a Uterine Leiomyosarcoma: The First Case and Review of Literature

Author(s): Marinaccio M, Giannoccaro A, Marzullo A, d’Amati A, Messina R, de Gennaro L, Cicinelli E, Mastronardi M

Uterine leiomyosarcoma is a rare malignancy with poor prognosis that occurs during pre- and peri-menopause. Metastatic spread in uterine leiomyosarcoma is common, but intradural spinal cord metastases is a very rare event, and, for this reason, there is no standard treatment. We report the case of a 58-years-old woman with onset symptoms related to intradural extramedullary metastasis and no gynecological signs. She underwent dorsal laminectomy followed by chemotherapy with gemcitabine and docetaxel and radiotherapy. Although she is suffering from a very serious illness, she is currently in good general condition. Some studies believe that the mutation of HRD and BRCA will be a therapeutic target in the future