Study of the Toxicity and Antiviral Effect of Natural Compounds Extracted from Pseudospinx Tetrio and Allamanda Cathartica on Sars-Cov-2 Infection

Author(s): Linda MATIGNON, Nathalie GROS, Richmond Jean-François KABLAN, Muriel SYLVESTRE, Jean-Didier MARECHAL, Gerardo CEBRIAN-TORREJON and Laura BRELLE

Very present in the Caribbean, the leaves of Allamanda cathartica L. and the caterpillar Pseudospinx tetrio, are unexploited resources. However, they are known to have an interesting antimicrobial activity. In this short communication, we propose a way of valorization of these resources. Indeed, the antiviral effect conferred by the molecules extracted from Allamanda cathartica L. leaves and caterpillars are tested against a virus that has become strongly known in 2019, the SARS-CoV-2. Preliminary results against this virus are promising and highlighted by biological tests performed on organic or aqueous extracts.