May the SARS-COV2 OMICRON Variant Signal the End of the Pandemic – A Fibonacci Fractal analysis

Author(s): Jean-Claude Perez, Valère Lounnas, Megawaty Tan, Xavier Azalbert, Christian Perronne

The emergence of the Omicron variant of SARS-CoV2 identified first in South Africa was announced with anxiety in media following alarm and concern by many researchers in the scientific community and the WHO has declared it a variant of concern (VOC): “The discovery of a highly mutated coronavirus variant in South Africa has triggered a global scramble” [1]. The main reason for this turmoil is the exploding number of non-synonymous mutations in the gene coding the spike protein causing lungs and other organs cell entry. However, objectively, although this variant may be very contagious it has not yet demonstrated any particular killing capability as the WHO reports: “There is currently no information to suggest that symptoms associated with Omicron are different from those from other variants. Initially reported infections were among university students—younger individuals who tend to have a more mild disease—but understanding the level of severity of the Omicron variant will take days to several weeks” [2]. A report deposited on medRxiv indicates that the mRNA vaccine is 4 to 6 fold less neutralizing Omicron than for the wild-type virus [3]. Another report by the University of Hong Kong shows that it replicates considerably less in the lung tissue compared with bronchus which may diminish the lethality [4]. So the question we discuss here is the potential causes and effects of a heavy mutational rate on the virus contagiousness and infectiousness.