Malignant Epithelioid Peritoneal Mesothelioma Recurring after 5 years, Case Report and Literature Review

Author(s): Maureen Chbat, Mohamad Rakka, Alaa Haidar, Nada Sabbah, Selim Nasser, Claude Tayar, Ali Yousef

Malignant Peritoneal mesothelioma is a rare disease of the peritoneal lining and its aggressiveness vary depending on the biology of the tumor and the risk factors of the patient. We are reporting in the following case the history of a 69 years old gentleman working in a petrochemical area in Saudi Arabia, who developed an epithelioid malignant peritoneal mesothelioma with a peritoneal carcinoma index (PCI) of 26 and who had a completeness of cytoreduction of 0 (CC0) after neoadjuvant chemotherapy, sequential chemotherapy (SIC) cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC), only to witness and survive a recurrence of his cancer 5 years after, revealing itself in a severe intestinal obstruction. Epidemiology, causes, diagnosis, pathology, risk factors, treatment and prognosis of this disease will be discussed in our discussion, insisting on the importance of regular surveillance to detect an early relapse of the disease and improve survival.