Electronic Cigarettes Use During Pregnancy - Is it Safe or Not? A Literature Review

Author(s): Iana Malasevskaia, Ahmed Ali Al-Awadhi, Fatima Ali Raza

Recently, the use of e-cigarettes has increased highly rapidly, especially among middle school and high school students and pregnant women who are concerned about tobacco effects on baby’s health. There is little understanding of the effects of exposure to e-cigarette on human reproductive health, human development, or pregnant women. Human and animal data support that nicotine exposure during periods of development has multiple adverse health consequences, including impaired fetal brain, lung, cardiac development, and altered development of cerebral cortex and hippocampus in adolescents. However, the effects of e-cigarettes are completely unknown regarding human development.

Aim: In this article, we are reviewing the most recent findings on the effects of e-cigarettes during pregnancy and early life.

Method: A literature search in PMC, PubMed, Google, ResearchGate, MEDLINE and Google Scholar was carried out using the following keywords: “Electronic cigarettes”, “E-cigarettes and pregnancy”, “ENDS and pregnancy”. Study selection was in the language (English only), model (humans and animals), open accesses, and all types of studies were included as long as they were relevant to our study.

Limitation of study: While we were collecting the information for this review, there were some limitations. Our data was primarily obtained from articles with free full access and written in English language only. This review article is a traditional review and, therefore, does not follow the Standard Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for systematic reviews.

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